Tahitian Noni International Research

Tahitian Noni International Research

Many companies talk about research and science. But only Tahitian Noni International backs their products with more than a dozen peer-reviewed human clinical trials.
And while most study just one ingredient from their product, TNI's scientists use the same bottle that sits in your refrigerator—original, 100% authentic TAHITIAN NONI® Juice. From TNI's industry-leading noni research laboratory, to universities and hospitals around the world, the results are the same: TAHITIAN NONI® Juice works.
Clinical Studies - Immune System

immune

TAHITIAN NONI® Juice helps strengthen your immune system*

Without a variety of daily nutrients, the body's complex immune system won't always function properly. Our daily lives are filled with stresses and complications, which can contribute to weakening our immune system. Luckily for us, research shows that drinking TAHITIAN NONI® Juice can help support a healthy immune system.*

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Clinical Studies - Athletic and Sports Recovery

Numerous reports and personal testimonials from world-class athletes suggest that TAHITIAN NONI® Juice may assist in recovery from sports exertion and discomfort.* In addition, TAHITIAN NONI® Juice does not contain any substances banned by the World Anti-Doping Association.
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Clinical Studies - Cholesterol Friendly

TAHITIAN NONI® Juice helps maintain cholesterol at existing healthy levels*

In order to maintain a healthy cardiovascular system, you have to keep your cholesterol under control. In research presented to the American Heart Association, Dr. Anne Hirazumi-Kim indicated that drinking three to four ounces of TAHITIAN NONI® Juice daily helps sustain cholesterol at existing normal levels.*

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Clinical Studies - Super-Antioxidant

antioxidants

Antioxidants are vital to healthy living—they help boost the immune system and fight off harmful free radicals. In laboratory tests, TAHITIAN NONI® Juice has been shown to be rich in natural antioxidants that your body can easily use.*

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Clinical Studies - Cardiovascular System

cardiovascular

A healthy heart is essential to overall well-being, and numerous studies have demonstrated noni's ability to support a healthy cardiovascular system.*

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*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

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IMMUNE SYSTEM RESEARCH

1. Hirazumi, A., E. Furusawa, S. C. Chou, Y. Hokama.
"Anticancer Activity of Morinda citrifolia (Noni) on Intraperitoneally Implanted Lewis Lung Carcinoma in Syngeneic Mice." Proc. West. Pharmocol. Soc. 37: 145-146 (1994).

2. Hirazumi, Anne, Eiichi Furusawa.
"An Immunomodulatory Polysaccharaide-Rich Substance from the Fruit Juice of Morinda citrifolia (Noni) with Antitumour Activity." Phytotherapy Research 13, 380-387 (1999).

3. Furusawa, Eiichi, Anne Hirazumi, Stephen Story, Jarakae Jensen.
"Antitumour Potential of a Polysaccharaide-rich Substance from the Fruit Juice of Morinda citrifolia (Noni) on Sarcoma 180 Ascites Tumour in Mice." Phytother, Res. 17, 1158-1164 (2003).

4. Wong, Desmond K.W., MD.
"Are Immune Responses Pivotal to Cancer Patient's long term survival? Two Clinical Case-Study Reports on the Effects of Morinda citrifolia (Noni)." Hawaii Medical Journal, Vol. 63, (June 2004).

5. Liu, Guangming. Ann Bode, Wei-Ya Ma, Shengmin Sang, Chi-Tang Ho, Zigang Dong.
"Two Novel Glycosides from the Fruits of Morinda Citrifolia (Noni) Inhibit AP-1 Transactivation and Cell Transformation in the Mouse Epidermal JB6 Cell Line." Cancer Research 61, 5749-5756 (2001).

6. Hirazumi, A. E. Furusawa, S.C. Chou, Y. Hokama.
"Immunomodulation Contributes to the Anticancer Activity of Morinda citrifolia (noni) Fruit Juice." Proc. West. Pharmacol. Soc. 39: 7-9 (3996).

7. Arpornsuwan, Teerakul and Tadsanee Punjanon.
"Tumor Cell-Selective Antiproliferative Effect of the Extract from Morinda citrifolia Fruits." Phytother. Res. 20:515-517 (2006).

8. Brooks, V.J. J. Xu, J. Cai, S.F. Peek, T. Schriver, R.G. Godbee, R.D Schultz, B.J. Darien.
"Enhanced Mononuclear Phagocytic Activity of Gram-Negative Bacteria in Calves Fed Morinda Cintrifolia (Tahitian Noni) Puree."

9. Chjen-Cheng Chen, Dong-Bor Yeh, Shih-Ying Chen.
"Study on the extracts of Morinda citrifolia protection against oxidative damage to human blood cells." Dept. of Biotechnology and Dept. of Health and Nutrition, Chia Nan University of Pharmacy and Science, Taiwan.

10. J. Xu, A.C. McSloy, B.K. Anderson, R.G. Godbee, S.F. Peek, B.J. Darien.
"Tahitian Noni Equine Essentials: A Novel and Anti-Inflammatory and a COX-2 Inhibitor which Regulates LPS-Induced Inflammatory Mediator Expression in Equine Neonatal

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ATHLETIC AND SPORTS RECOVERY RESEARCH

1. Improves athlete endurance
This study by Tahitian Noni scientists shows people who drink TAHITIAN NONI® Juice experience a 21% increase in athletic performance, due to high antioxidant activity. Juice drinkers were able to run longer, faster and with more endurance than those who did not drink TAHITIAN NONI® Juice.

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CHOLESTEROL RESEARCH

1. May lower cholesterol and triglycerides in adult smokers
In this study presented to the American Heart Association, TAHITIAN NONI® Juice was given to 106 adult smokers ranging from 20-60 years in age. After one month of drinking the juice, researchers found that the average cholesterol level of these TAHITIAN NONI® Juice drinkers fell from 235.2 to 190.2. Another group which received a placebo experienced no significant change.

2. A complete review of TAHITIAN NONI® Juice
Noni has been used by Tahitians for thousands of years, but only recently has it become a popular item for mainstream consumers. This popularity has raised several questions about the noni fruit, and in this study Tahitian Noni scientists conduct several tests to verify that the noni fruit and TAHITIAN NONI Juice are, in fact, safe for consumption.

3. Wang, Mian-Ying, Eric Henlye, Jeanette Nolting, Alexandra Cheerva, Jarakae Jensen, Gary Anderson, Diane Nowicki, Stephen Story.
"The Effects of Morinda Citrifolia (Noni) Fruit Juice on Serum Cholesterol and Triglyceride in Current Smokers." Circulation 113, 301-381 (2006).

4. Wang, Mian-Ying, Diane Nowicki, Gary Anderson, Alexandra Cheerva, Jarakae Jensen.
"The heart protection study: improvement of lipoprotein profiles in current smokers receiving Morinda citrifolia (Noni) fruit juice." Circulation 109, 71-144 (2004)..

5. Palu, 'Afa Kehaati, Brett Justin West, Jarakae Jensen, Bing-Nan Zhou.
"Morinda citrifolia L. Noni has Cholesterol Lowering Potential. Folk Botanical Wisdom: Towards Global Markets. June 5-9, 2006.

6. West, B.J., C.J. Jensen, L. Westendorf, L.D. White.
"A Safety Review of Noni Juice." J. Food Sci. 2006. 71:R100-R106.

7. Wang, Mian-Ying, Gary Anderson, Diane Nowicki, Jarakae Jensen.
"Cardiovascular Disease Prevention with Morinda Citrifolia (Noni) by Improving Lipoprotein Profiles in a Chronic Liver Injury Model Induced by Carbon Tetrachloride in Female SD Rats." Circulation Vol. 111, 40-88 (2005).

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ANTIOXIDANT RESEARCH

1. Wang, M.Y., C. SU,
"Cancer Preventive Effect of Morinda citrifolia (Noni)." Annals New York Academy of Sciences.

2. Su, Bao-Ning, Alison d. Pawlus, Hyun-Ah Jung, William J. Keller, Jerry L. McLaughlin, A. Douglas Kinghorn.
"Chemical Constituents of the Fruits of Morinda citrifolia (Noni) and Their Antioxidant Activity." J. Nat. Prod., 68, 592-595 (2005).

3. Kamiya, Kohei, Toyei Tanaka, Hanani Endang, Mansur Umar, Toshiko Satake.
"Chemical Constituents of Morinda citrifolia Fruits Inhibit Copper-Induced Low-Density Lipoprotein Oxidation." Journal of Agricultural and Food Chemistry, 2004.

4. Poster Abstracts. Subsection: Wang, M.Y., S. Su, A.D. Nowicki, J.Jensen, and G. Anderson.
"Morinda citrifolia and Cancer Prevention." Available online at http://www.jca.gr.jp/pdf/aj7ps_a.pdf (p. A23).

5. Wang, M. Y., A. Cheerva, C. Su, J. Jensen, D. Nowicki, G. Anderson, S. Jensen, J. W. Fritz.
"Protective Effects of Morinda citrifolia (Noni) on Plasma SAR and LPO in Current Smokers." XI Biennial Meeting of the Society for Free Radical Research International, 2002. A summary of this study is available online at http://www.chinaphar.com/1671-4083/23/1127.pdf (p. 1136).

6. Zin, Z. Mohd, A. Abdul Hamid, A. Osman, N. Saari,
"Antioxidative activities of chromatographic fractions obtained from root, fruit, and leaf of Mengkudu (Morinda citrafolia L.)." Food Chemistry 94, 169-178 (2006).

7. Ying-Mian, Wang, Brett J. West, C. Jarakae Jensen, Diane Nowicki, Su Chen, Afa K. Palu, Gary Anderson,
"Morinda citrifolia (Noni): A literature review and recent advances in Noni research." Acta Pharmacologica Sinica, 1135-1136 (2002).

8. Wang, Mian-Ying, Eric Henley, Lin Peng, Vicki Weidenbacher-Hoper, Joella Warner, Nawal Lutfiyya, Gary Anderson.
"Morinda citrifolia Reduces Cancer Risk in Current Smokers." AACR-JCA Joint International Conference (January 21-25, 2007). Available online here.

9. Zin, Z. Mohd.
"Isolation and Identification of Antioxidative Compound from Fruit of Mengkudu (Morinda citrifolia)." International Journal of Food Properties, Vol. 10, 363-373 (2007).

10. S. Vimala & Mohd. Illham Adenan.
"Malaysian Tropical Forest Medicinal Plants: A Source of Natural Antioxidants." Journal of Tropical Forest Products 5(1): 32-38 (1999).

11. Park, YK, E. Park, Kim JS, Kang MH.
"Daily grape juice consumption reduces oxidative DNA damage and plasma free radical levels in healthy Koreans." Mutat. Res. 529 (1-2): 103 (Feb 2004).

12. O'Byrne, Dawn J., Sridevi Devaraj, Scott M. Grundy, and Ishwarlal Jialal.
"Comparison of the antioxidant effects of Concord grape juice favonoids and a-tocopherol on markers of oxidative stress in healthy adults." Am. J. Clin. Nutr. 76: 1367-74 (2002).

13. Prior, R.L., Gu L., Wu X., Jacob R. A., Sotoudeh G., Kader A.A., Cook, R. A.
"Plasma antioxidant capacity changes following a meal as a measure of the ability of a food to alter in vivo antioxidant status." J. Am. Coll. Nutr. 26(2): 170-81 (2007).

14. Harada, Shinichi. Wakako Harnabe, Kohei Kamiya, Toshiko Stake, Shogo Tokuyama.
"The preventive effect of the juice of Morinda citrifolia against the ischemic brain injury." Journal of Pharmacological Sciences, Vol. 103, Supp. 1:228P (2007).

15. Palu, Afa Kehaati.
"Tahitian Noni Juice: Its Antioxidant Capacity is Only a Part of the Repertoires of its Scientifically Proven Health Benefits." Tahitian Noni International Research Center, American Fork, Utah 2004.

16. Brett J. West, C. Jarakae Jensen.
Noni juice increases athlete endurance via antioxidant mechanism. Poster # 208. Joint Northwest and Rocky Mountain Regional Meeting of the American Chemical Society. June 17, 2008. Park City, Utah, USA.

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CARDIOVASCULAR RESEARCH

1. A complete review of TAHITIAN NONI® Juice
Noni has been used for thousands of years, but only recently has it become a popular item for mainstream consumers. This popularity has raised several questions about the noni fruit, and in this study Tahitian Noni scientists conduct several tests to verify that the noni fruit and TAHITIAN NONI Juice are, in fact, safe for consumption.

2. Palu, 'AK, Santiago, RA, West, BJ, et al.
The Effects of Morinda citrifolia L. Noni on High Blood Pressure: A Mechanistic Investigation and Case Study. American Chemical Society Symposia Series (In press).

3. Wang, M-Y, Nowicki, D, Anderson, G.
The Heart Protection Study: Improvement of Lipoprotein Profiles in Current Smokers Receiving Morinda citrifolia (Noni) Fruit Juice. 2004. Circulation, J Am Heart Assoc, 109: 71—144 (Abs #P93).

4. West BJ, Jensen CJ, Westendorf J, and White LD.
A Safety Review of Noni Fruit Juice. Journal of Food Science 2006 October; 71(8): R100-R106.

5. Kamiya K, Tanaka Y, Endang H, Umar M, Satake T.
Chemical constituents of Morinda citrifolia fruits inhibit copper-induced low-density lipoprotein oxidation. J Agric Food Chem. 2004 Sep 22; 52(19): 5843-8.

6. Ayanbule F, Wang MY, Peng L, Nowicki J, Anderson G, Nowicki D.
Antithrombotic Effect of Morinda citrifolia (Noni) Fruit Juice on the Jugular Vein Thrombosis Induced by Ferric Chloride in Male Adult SD Rats. Arterioscler. Thromb. Vasc. Biol. 2006; 26; e104.

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*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Tahitian Noni International Independent Product Consultant

TAHITIAN NONI®, Tahiti Trim® Plan 40®, Hoa®, Moéa®, TePoemä®, Equine Essentials™, Canine Essentials® , TAHITIAN NONI® n-Core™, Tahitea™, Skin Supplement™, Smart Extracts®, HIRO™, and NatureBorn™ are all trademarks of TAHITIAN Noni International Inc.